http://hexus.net/tech/items/storage/93287-patriot-announces-2tb-ignite-ssd/

Patriot Announces 2TB Ignite SSD

TAIPEI, Taiwan – May 30, 2016 – Patriot, a leading manufacturer of high performance computer memory, SSDs, gaming peripherals, consumer flash storage solutions and mobile accessories, today introduced a 2TB addition to its performance solid state drive (SSD)  line, the Ignite. Patriot looks to fulfill the ever-growing demand for increased amounts of storage in consumer PCs.

Patriot originally launched the Ignite SSD in January of 2015 with top performing speeds and capacities of 480GB and 960GB. Since then, Patriot has added the addition of a 240GB capacity and now a multi-terabyte capacity to tackle even the most taxing data loads. With the Ignite 2TB SSD consumers can load an entire library of PC games to their rig without having to unload and load games when storage runs out.

Continuing to utilize the Phison S10 controller the 2TB Ignite reaches sequential read speeds of up to 560MB/s and write speeds of up to 500MB/s, to diminish lag while loading content to the drive. Designed in a 2.5” form factor, the 2TB Ignite has a SATA III 6.0Gb/s interface and is backwards compatible with SATA II making it the ideal upgrade for those looking for a complete solution for a lack of storage space and a PC refresh to breathe life back into an old system.

“The 2TB Ignite offers consumers the fast transfer speeds expected of our Ignite line along with the extra capacity required by power users,” Said Les Henry, VP of Engineering at Patriot. “These drives are the perfect solution for those users with very large game and video libraries as well as systems being used for cloud storage.”

The Ignite 2TB is  Compatible with Windows® XP, Windows Vista®, Windows, 7, Windows® 8, Windows® 8.1, Windows® 10, Mac OS X, and Linux systems. Backed by Patriot’s award winning build quality and 3-year warranty; the Patriot Ignite will deliver one of the most reliable choices in SSDs.

Availability

The 2TB Ignite SSD will be available for purchase, worldwide, starting in the 4th Quarter of 2016. For more details visit: https://patriotmemory.com.

About Patriot

Patriot is a leading manufacturer of high performance, enthusiast memory modules, SSDs, flash storage, gaming peripherals and mobile accessories. Founded in 1985 and headquartered in Fremont, CA, USA, Patriot is committed to technology innovation, customer satisfaction and providing the best price for performance on the market. Patriot products have become world renown for their extreme performance, reliability and innovation. Patriot sells its products through original equipment manufacturers, retailers, e-tailers and distributors throughout the world with operations in North America, South America, Asia and Europe.

http://cleantechnica.com/2016/05/30/lithium-ion-battery-expert-jeff-dahn-start-tesla-motors/

Lithium-Ion Battery Expert Jeff Dahn About To Start At Tesla Motors

As part of its ongoing expansion efforts following the great success of the Model 3 reveal, andas reported a year ago, Tesla has secured an exclusive contract with the noted battery researcher Jeff Dahn (of Dalhousie University in Nova Scotia).

The new contract begins on June 8th, and will see Dahn working to increase the performance of the company’s (already cutting-edge) batteries. Dahn will reportedly be doing “whatever it takes” to improve performance.

Jeff Dahn was quoted by Quartz as saying that the research goals for his work with Tesla are pretty much the standard ones in the industry — high energy density, low cost, and a long working life. The “whatever it takes” mentioned above apparently originated in a conversation that Dahn had with Tesla’s battery division head Kurt Kelty.

“Those are the goals, and that’s how we’re going to do it,” Dahn commented. “We’re open to anything that makes sense.”

 

Dahn is certainly an interesting hire. Especially when considering that his most famous work to date has been with regard to a different battery chemistry (NMC) than the one that Tesla uses currently (NCA). Interesting announcements are now probably already in the offing…

As mentioned at the start of the article, Tesla’s been on something of a hiring spree lately — following the speeding up of Model 3 production plans, and some internal housecleaning. For information on those hires and departures, see:

Tesla’s New VP Of Vehicle Production Is Ex-Audi Production Head (For A4, A5, & Q5) Peter Hochholdinger

Faraday Future Hires Tesla’s Former VP Of Government Relations & Deputy General Counsel

http://www.kurzweilai.net/how-to-erase-bad-memories-and-enhance-good-ones

How to erase bad memories and enhance good ones

May 27, 2016

Mice normally freeze in position as a response to fear, as shown here under control condition (center row): fear conditioning induces freezing behavior in response (recall) to exposure to the conditioned stimulus (tone), but the freezing response normally decreases (extinction) following several days of multiple tone exposures (the mice get used to it). However, enhancing release of acetylcholine (blue light) to the amygdala during conditioned fear training resulted in continued freezing behavior 24 hours later and persisted over long periods of time (extinction). In contrast, reducing acetylcholine (yellow light) during the initial training period reduced the freezing behavior (during recall) and led to greater retention of the extinction learning (reduced freezing). (credit: Li Jiang et al./Neuron)

Imagine if people with dementia could enhance good memories or those with post-traumatic stress disorder could wipe out bad memories. A Stony Brook University research team has now taken a step toward that goal by manipulating one of the brain’s natural mechanisms for signaling involved in emotional memory: a neurotransmitter called acetylcholine.

The region of the brain most involved in emotional memory is thought to be the amygdala. Cholinergic neurons that reside in the base of the brain — the same neurons that appear to be affected early in cognitive decline — stimulate release of acetylcholine by neurons in the amygdala, which strengthens emotional memories.

Because fear is a strong and emotionally charged experience, Lorna Role, PhD, Professor and Chair of the Department of Neurobiology and Behavior, and colleagues used a fear-based memory model in mice to test the underlying mechanism of memory and the specific role of acetylcholine in the amygdala.

A step toward reversing post-traumatic stress disorder

Be afraid. Be very afraid. Optogenetic stimulation with blue light. (credit: Deisseroth Laboratory)

To achieve precise control, the team used optogenetics, a research method using light, to stimulate specific populations of cholinergic neurons in the amygdala during the experiments to release acetylcholine. As noted in previous studies reported on KurzweilAI, shining blue (or green) light on neurons treated with light-sensitive membrane proteins stimulates the neurons while shining yellow (or red) light inhibits (blocks) them.

So when the researchers used optogenetics with blue light to increase the amount of acetylcholine released in the amygdala during the formation of a traumatic memory, they found it greatly strengthened fear memory, making the memory last more than twice as long as normal.

But when they decreased acetylcholine signaling (using yellow light) in the amygdala from a traumatic experience — one that normally produces a fear response — they could actually extinguish (wipe out) the memory.

Role said the long-term goal of their research is to find ways — potentially independent of acetylcholine (or drug administration) — to enhance or diminish the strength of good memories and diminish the bad ones.

Their findings are published in the journal Neuron. The research was supported in part by the National Institutes of Health.


Abstract of Cholinergic Signaling Controls Conditioned Fear Behaviors and Enhances Plasticity of Cortical-Amygdala Circuits

We examined the contribution of endogenous cholinergic signaling to the acquisition and extinction of fear- related memory by optogenetic regulation of cholinergic input to the basal lateral amygdala (BLA). Stimulation of cholinergic terminal fields within the BLA in awake-behaving mice during training in a cued fear-conditioning paradigm slowed the extinction of learned fear as assayed by multi-day retention of extinction learning. Inhibition of cholinergic activity during training reduced the acquisition of learned fear behaviors. Circuit mechanisms underlying the behavioral effects of cholinergic signaling in the BLA were assessed by in vivo and ex vivo electrophysiological recording. Photostimulation of endogenous cholinergic input (1) enhances firing of putative BLA principal neurons through activation of acetylcholine receptors (AChRs), (2) enhances glutamatergic synaptic transmission in the BLA, and (3) induces LTP of cortical-amygdala circuits. These studies support an essential role of cholinergic modulation of BLA circuits in the inscription and retention of fear memories.

http://www.kurzweilai.net/automated-top-down-design-technique-simplifies-creation-of-dna-origami-nanostructures

Automated top-down design technique simplifies creation of DNA origami nanostructures

Nanoparticles for drug delivery and cell targeting, nanoscale robots, custom-tailored optical devices, and DNA as a storage medium are among the possible applications
May 27, 2016

The boldfaced line, known as a spanning tree, follows the desired geometric shape of the target DNA origami design method, touching each vertex just once. A spanning tree algorithm is used to map out the proper routing path for the DNA strand. (credit: Public Domain)

MIT, Baylor College of Medicine, and Arizona State University Biodesign Institute researchers have developed a radical new top-down DNA origami* design method based on a computer algorithm that allows for creating designs for DNA nanostructures by simply inputting a target shape.

DNA origami (using DNA to design and build geometric structures) has already proven wildly successful in creating myriad forms in 2- and 3- dimensions, which conveniently self-assemble when the designed DNA sequences are mixed together. The tricky part is preparing the proper DNA sequence and routing design for scaffolding and staple strands to achieve the desired target structure. Typically, this is painstaking work that must be carried out manually.

The new algorithm, which is reported together with a novel synthesis approach in the journal Science, promises to eliminate all that and expands the range of possible applications of DNA origami in biomolecular science and nanotechnology. Think nanoparticles for drug delivery and cell targeting, nanoscale robots in medicine and industry, custom-tailored optical devices, and most interesting: DNA as a storage medium, offering retention times in the millions of years.**

Shape-shifting, top-down software

Unlike traditional DNA origami, in which the structure is built up manually by hand, the team’s radical top-down autonomous design method begins with an outline of the desired form and works backward in stages to define the required DNA sequence that will properly fold to form the finished product.

“The Science paper turns the problem around from one in which an expert designs the DNA needed to synthesize the object, to one in which the object itself is the starting point, with the DNA sequences that are needed automatically defined by the algorithm,” said Mark Bathe, an associate professor of biological engineering at MIT, who led the research. “Our hope is that this automation significantly broadens participation of others in the use of this powerful molecular design paradigm.”

The algorithm, which is known as DAEDALUS (DNA Origami Sequence Design Algorithm for User-defined Structures) after the Greek craftsman and artist who designed labyrinths that resemble origami’s complex scaffold structures, can build any type of 3-D shape, provided it has a closed surface. This can include shapes with one or more holes, such as a torus.

A simplified version of the  top-down procedure used to design scaffolded DNA origami nanostructures. It starts with a polygon corresponding to the target shape. Software translates a wireframe version of this structure into a plan for routing DNA scaffold and staple strands. That enables a 3D DNA-based atomic-level structural model that is then validated using 3D cryo-EM reconstruction. (credit: adapted from Biodesign Institute images)

With the new technique, the target geometric structure is first described in terms of a wire mesh made up of polyhedra, with a network of nodes and edges. A DNA scaffold using strands of custom length and sequence is generated, using a “spanning tree” algorithm — basically a map that will automatically guide the routing of the DNA scaffold strand through the entire origami structure, touching each vertex in the geometric form once. Complementary staple strands are then assigned and the final DNA structural model or nanoparticle self-assembles, and is then validated using 3D cryo-EM reconstruction.

The software allows for fabricating a variety of geometric DNA objects, including 35 polyhedral forms (Platonic, Archimedean, Johnson and Catalan solids), six asymmetric structures, and four polyhedra with nonspherical topology, using inverse design principles — no manual base-pair designs needed.

To test the method, simpler forms known as Platonic solids were first fabricated, followed by increasingly complex structures. These included objects with nonspherical topologies and unusual internal details, which had never been experimentally realized before. Further experiments confirmed that the DNA structures produced were potentially suitable for biological applications since they displayed long-term stability in serum and low-salt conditions.

Biological research uses

The research also paves the way for designing nanoscale systems mimicking the properties of viruses, photosynthetic organisms, and other sophisticated products of natural evolution. One such application is a scaffold for viral peptides and proteins for use as vaccines. The surface of the nanoparticles could be designed with any combination of peptides and proteins, located at any desired location on the structure, in order to mimic the way in which a virus appears to the body’s immune system.

The researchers demonstrated that the DNA nanoparticles are stable for more than six hours in serum, and are now attempting to increase their stability further.

The nanoparticles could also be used to encapsulate the CRISPR-Cas9 gene editing tool. The CRISPR-Cas9 tool has enormous potential in therapeutics, thanks to its ability to edit targeted genes. However, there is a significant need to develop techniques to package the tool and deliver it to specific cells within the body, Bathe says.

This is currently done using viruses, but these are limited in the size of package they can carry, restricting their use. The DNA nanoparticles, in contrast, are capable of carrying much larger gene packages and can easily be equipped with molecules that help target the right cells or tissue.

The most exciting aspect of the work, however, is that it should significantly broaden participation in the application of this technology, Bathe says, much like 3-D printing has done for complex 3-D geometric models at the macroscopic scale.

Hao Yan directs the Biodesign Center for Molecular Design and Biomimetics at Arizona State University and is the Milton D. Glick Distinguished Professor, College of Liberal Arts and Sciences, School of Molecular Sciences at ASU.

* DNA origami brings the ancient Japanese method of paper folding down to the molecular scale. The basics are simple: Take a length of single-stranded DNA and guide it into a desired shape, fastening the structure together using shorter “staple strands,” which bind in strategic places along the longer length of DNA. The method relies on the fact that DNA’s four nucleotide letters—A, T, C, & G stick together in a consistent manner — As always pairing with Ts and Cs with Gs.

The DNA molecule in its characteristic double stranded form is fairly stiff, compared with single-stranded DNA, which is flexible. For this reason, single stranded DNA makes for an ideal lace-like scaffold material. Further, its pairing properties are predictable and consistent (unlike RNA).

** A single gram of DNA can store about 700 terabytes of information — an amount equivalent to 14,000 50-gigabyte Blu-ray disks — and could potentially be operated with a fraction of the energy required for other information storage options.


Biodesign Institute at ASU | DNA Origami


Abstract of Designer nanoscale DNA assemblies programmed from the top down

Scaffolded DNA origami is a versatile means of synthesizing complex molecular architectures. However, the approach is limited by the need to forward-design specific Watson-Crick base-pairing manually for any given target structure. Here, we report a general, top-down strategy to design nearly arbitrary DNA architectures autonomously based only on target shape. Objects are represented as closed surfaces rendered as polyhedral networks of parallel DNA duplexes, which enables complete DNA scaffold routing with a spanning tree algorithm. The asymmetric polymerase chain reaction was applied to produce stable, monodisperse assemblies with custom scaffold length and sequence that are verified structurally in 3D to be high fidelity using single-particle cryo-electron microscopy. Their long-term stability in serum and low-salt buffer confirms their utility for biological as well as nonbiological applications.

http://news.ubc.ca/2016/05/30/dna-studied-to-solve-brain-disease/

DNA studied to solve brain disease

UBC researchers are identifying the genetic underpinning of intellectual disabilities by sampling DNA from chronically sick children, according to Vancouver 24 Hours.

The study is the first of its kind, said UBC principal investigator Dr. Clara van Karnebeek, a biochemical geneticist and pediatrician at B.C. Children’s Hospital.

“The conventional testing was looking at the chromosomes and also doing some functional testing, looking at chemicals in the blood, are there signs of an energy problem? And then going back to the genes to see if we can find a mutation,” said van Karnebeek.

http://news.ubc.ca/2016/05/30/using-smartphone-excessively-gives-you-faux-adhd/

Using smartphone excessively gives you faux-ADHD

A University of Virginia-UBC study links smartphone alerts to symptoms of attention deficit hyperactivity disorder, reportsQuartz.

“The results were clear: more frequent phone interruptions made people less attentive and more hyperactive,” wrote study author Kostadin Kushlev, a psychology research scientist at the University of Virginia, who led the study with UBC colleagues.

The study followed 221 UBC students and found that when they had their phones’ notification alerts on and kept their phones within reach, they were more inattentive and hyperactive than when interruptions were kept to a minimum.

 

http://www.australianetworknews.com/wwdc-2016-5-top-ios-10-iphone-ipad-rumours/

WWDC 2016: 5 Top iOS 10, iPhone, iPad Rumours

 Apps

iOS 10 would have the ability to cover Apple’s stock apps from your Home screen. According to reports, Apple is planning to introduce a standalone app that would give a location other than Siri and third-party apps for HomeKit.

The app would manage accessories using the platform. Reports even suggest that Apple is working on a way to provide users paid subscription content via its News app. It was launched last year along with iOS 9.

App Store

VP of Worldwide Marketing of Apple, who has recently taken over another responsibility of App Store, have confirmed that the company would solve the long-standing issues, especially with search and discovery features.

Apple Music & iTunes

Apple will overhaul the Apple Music as per the report filed by 9to5 Mac, earlier this month. Currently, Apple is working on a new, mostly black and white UI service, noted Mark Gurman. It was criticized by users and press, despite that it managed to hit 13 million paying subscribers in its first year of availability.

iCloud and Security

After the FBI unlocking controversy earlier this year, rumours suggested that Apple will be rolling out stronger iCloud backup encryption as well as iPhone security features. The upcoming WWDC 2016 event could see new and improved security features as part of iOS 10 launches.

Apple Pay & Touch ID

Apple is trying to enhance the Apple Pay support and bring about a person-to-person payments feature along with ATM withdrawal support. The company is also planning to further expand the payments service to more countries. Reports noted that Mac can be unlocked with iPhone’s Touch ID fingerprint sensor.

http://www.thehindu.com/sci-tech/health/researchers-develop-novel-technology-for-customised-tablets/article8660485.ece

Researchers develop novel technology for customised tablets

Researchers have found a novel way to make personalised medicine cheaper and easier by combining the myriad of pills you need to take for your ailment in just one tablet.

The medication will only need to be taken once a day and the drug will be slowly released throughout the day at different rates to treat the illness. It will also enable doctors to easily make tablets on the spot that are tailored to each patient’s needs, researchers said.

The new method of tablet fabrication designed by Soh Siow Ling and Sun Yajuan from National University of Singapore (NUS) can make customisable pills that release drugs with any desired release profiles.

Releasing drugs in a timely manner is important for optimal therapeutic effect in the human body. Different types of clinical circumstances may call for different types of timed release of drugs, researchers said.

While there are some existing tablet—production methods, including three-dimensional (3D) printing, that can allow certain flexibility, they have their limitations — low dosage, release profiles that are non—continuous, or the drugs are released in a large burst in the initial stage, and poor durability of the tablet given its quick breakdown, they said.

These methods are also only able to fabricate tablets that release drugs with a limited type of profiles.

“For a long time, personalised tablets has been a mere concept as it was far too complex or expensive to be realised,” said Soh.

“This new tablet fabrication method is a game changer – it is technically simple, relatively inexpensive and versatile,” he said.

“It can be applied at individualised settings where physicians could produce customised pills on the spot for patients, or in mass production settings by pharmaceutical companies,” he added.

Instead of manufacturing the drug tablet by printing layer by layer, the drug tablet consists of three distinct components, including a polymer containing the drug in a specifically designed shape that will determine the rate of release of the drug, researchers said.

For example, a 5-prong shape will allow the drug to be released in five pulses over time. By adjusting the shape of the drug—containing polymer, it is thus possible to release drugs at any desired rate, they said.

Using this system, a doctor only needs to draw the desired release profile in a computer software to generate a template for making tablets specific to a patient’s treatment, which can then be used to easily produce the desired pills using a 3D printer, researchers said.

The system is easy to use and does not involve any complex mathematical computation whenever a new release profile is needed. The fully customisable system is able to create a template to print tablets for any release profile, they said.

http://phys.org/news/2016-05-nasa-inflates-room-space.html

NASA inflates spare room in space

NASA on Saturday successfully expanded and pressurized an add-on room at the International Space Station two days after aborting the first attempt when it ran into problems.

This image obtained May 28, 2016 courtesy of NASA shows an inflatable add-on room, known as the Bigelow Expandable Activity Modu

This image obtained May 28, 2016 courtesy of NASA shows an inflatable add-on room, known as the Bigelow Expandable Activity Module (BEAM), at the International Space Station

The flexible habitat, known as the Bigelow Expandable Activity Module (BEAM), completed slowly extending 67 inches (170 centimeters) at 4:10 pm (2010 GMT) following more than seven hours during which astronaut Jeff Williams released short blasts of air into the pod’s walls from the orbiting lab using a manual valve.

After the expansion was completed, he opened eight air tanks inside BEAM, pressurizing the pod to a level close to the space station’s 14.7 pounds per square inch.

“The module is fully expanded at this point and fully pressurized,” NASA spokesman Daniel Huot said. “A very successful day today with the expansion of the first expandable human-rated habitat to ever be flown into space.”

Astronauts will now perform a series of tests to ensure the pod does not leak air and conduct other preparations before entering it through the station’s Tranquility module for the first time in approximately a week, NASA said.

The inflation process may be better described as “unfolding” since it takes very little air to bring the pod to full size, experts said. Only about 0.4 pounds per square inch (psi) is needed to expand BEAM to its full shape.

The expansion caused a popping sound not unlike that of popcorn as the structure slowly filled out, live video feed from the space station on NASA television showed.

NASA is testing expandable habitats astronauts might use on the Moon or Mars in the coming decades.

Efforts to inflate the flexible habitat got under way around 9 am (1300 GMT) after the first attempt failed on Thursday because of too much friction between the pod wall’s fabrics, possibly because it had been left packed longer than originally planned.

Astronauts are expected to re-enter the module several times a year throughout the two-year technology demonstration to retrieve sensor data and assess conditions inside the unit, including how well it protects against space radiation, the US space agency said.

Bigelow Aerospace developed the first-of-its-kind habitat as part of an $18 million contract with NASA.

Fully expanded, the module is 13 feet long (four meters) by 10.5 feet (3.23 meters) wide.

Expandable habitats’ benefit lies in the little space they take up in spacecrafts’ cargo holds while providing greater living and working space once inflated.

But key questions that remain to be answered include how well such pods would protect people against solar radiation, debris and the temperature extremes of space.

http://www.midwestproducer.com/news/agri-tech/study-genetically-modified-crops-do-not-add-to-human-health/article_d5d114e6-2393-11e6-8d2f-a31847515bb1.html

Study: Genetically modified crops do not add to human health risks

One of the nation’s premier scientific bodies says it has found no evidence that genetically modified crops are bad for human health.

In a 400-page report released May 17, the National Academies of Sciences, Engineering, and Medicine says its review of nearly 900 studies and years of disease data showed no increase in health risks due to the consumption of genetically modified food.

The group, however, noted that expert scientific bodies do not agree about the cancer-causing potential of glyphosate, an herbicide that’s often paired with genetically engineered crops.

It also pointed out the use of genetically modified organisms, or GMOs, has led to increases in weed and pest resistance and called for incentives and regulations to push farmers toward practices to delay the evolution of resistance in weeds and pests.

The report advocated for similar regulatory treatment of plants whose genes have been altered in any way — either through genetic engineering or conventional breeding techniques. USDA and EPA partially decide which plants to regulate based on the process by which their genes were altered, the report says, and new methods of genetic manipulation may fall outside existing regulatory regimes.

Any genetic alteration has the potential for unintended consequences, the report said, and the product, not the process, should be the driver behind regulatory review.

Genetically modified crops were widely adopted in U.S. agriculture in the 1990s, mainly by incorporating genes resistant to pests and herbicides. Monsanto, based in suburban St. Louis, was one of the early developers of genetically modified crops, engineering soybeans and corn to be resistant to glyphosate, sold under the brand Roundup.

But as their use has grown, concerns over their safety have persisted, leading some food manufacturers and restaurants to disclose their use or tout products free of GMOs. Vermont will begin requiring labeling of GMOs this summer, and other states have tried to enact similar laws.

Monsanto and other big agriculture and food companies, however, have fought the efforts, arguing that labeling food would confuse consumers and lead to an expensive patchwork of state regulations.

Many people are concerned that GMOs are partly to blame for cancer, obesity, gastrointestinal tract illnesses, kidney disease, allergies and autism spectrum disorders, the National Academies said.

It reviewed disease registries in the U.S. and Canada, where GMOs have been a regular part of the diet since the 1990s, and the United Kingdom and Western Europe, where GMOs are not widely consumed.

It found no difference in the increase or decrease of specific health problems after the introduction of GMO foods and the associated increase in glyphosate.

Even without evidence of health effects from existing GMO use, the study committee’s chair, North Carolina State University entomology professor Fred Gould, said continued scrutiny is necessary because of the possibility of “subtle” effects showing up later. He compared it to changing consensus over the years on dietary guidelines, such as the health benefit of eggs or how much salt is healthy.

“It’s been 20 years, maybe it will take 40 years to show up,” he said during a briefing on the report.

The report did acknowledge there is “ongoing debate about potential carcinogenicity of glyphosate in humans.” While a report in March 2015 from the International Agency for Research on Cancer listed the herbicide as “probably” carcinogenic to humans, other regulatory agencies have not found a link to cancer, including the EPA, Canada’s health agency and the European Food Safety Authority. On Monday, experts from the United Nations Food and Agriculture Organization and World Health Organization concluded a review that found glyphosate is “unlikely to pose a carcinogenic risk to humans.”

Matt Arnold, an analyst at Des Peres-based Edward Jones who follows Monsanto, said he doesn’t see the report swaying skeptics of GMOs, affecting consumer demand or influencing debates on state labeling laws. Critics will point to their pairing with herbicides, he said.

“The lack of evidence that genetically modified crops do cause harm is Monsanto’s strongest argument, and this report kind of bolsters that argument to some extent,” Arnold said. But “at the end of the day, it’s more ammo in a debate that will rage on as far as the eye can see.”

Monsanto, in a statement, said the report “underscores” the “science and safety” behind GMO crops.

“We believe this was a valuable analysis that brought together parties on all sides of the science who share different viewpoints about its promise and potential,” the company said.

When it came to social and economic effects, the National Academies said farmers who have adopted genetically engineered crops “generally had favorable economic outcomes.”

But it did dampen one of the big talking points espoused by Monsanto and other seed companies, namely that their GMO technologies are necessary in order to keep up with population growth. Even though pest-resistant crops have reduced farmers’ crop losses, there is no evidence that the adoption of GMOs in the 1990s sped up farm yield improvements beyond the pace they had been on in the preceding decades, the report found.

“We hear quite a few claims that we need genetically engineered crops to feed the world, and by using genetic engineering we can increase the rate by which we improve crop yield,” Gould said. “With the advent of (GMO) crops, we’re not seeing that all of a sudden we’re increasing the rate of increase.”

Going forward, the committee recommended investing in a number of different approaches, not just genetic engineering, to continue the improvements in farm yields.

While the report said it found no evidence of “cause-and-effect relationships” between genetically modified crops and environmental problems, it said “the complex nature of assessing long-term environmental changes often made it difficult to reach definitive conclusions.”

For instance, it said the scientific literature has not found a definitive link between the decline of monarch butterfly populations and glyphosate suppression of milkweed. Yet it noted that there is no consensus among researchers that “increased glyphosate use is not at all associated with decreased monarch populations.”

The National Academies, regarded as one of the country’s most prestigious scientific bodies, still drew criticism from groups opposed to the use of genetically engineered food.

Advocacy group Food and Water Watch released a report Monday that accused many of the study committee members of having worked with Monsanto or other companies with an interest in GMO use over the years. It said “millions of dollars” go to the National Academies from Monsanto and similar companies and questioned whether the public should trust the review.

“Corporate agribusinesses pour millions of dollars into our public universities, play a heavy hand in peer-reviewed scientific journals and seek to influence prestigious scientific bodies like the National Research Council,” Food and Water Watch wrote in a blog May 16 about the soon-to-be-released report. “We’ve asked the (National Research Council) many times to remove itself from this broken system of science, to step up and be a leader on the issue of conflicts of interest in GMO research.”

Gould said that funding for the report came from nonindustry sources and pointed to a special disclosure section. He said it’s important that groups like Food and Water Watch “keep pushing us to be as transparent as possible,” but he said he worried that some of the accusations would hinder dialogue about costs and benefits of GMO use.

“There’s a lot of talking points that go around from both sides,” Gould said. “And we’re kind of tired of that. We want to see a conversation.”

Jacob Barker is a reporter for the St. Louis Post-Dispatch.